Dibasic sodium phosphate dodecahydrate USP/Ph.Eur/BP PARENTEX PLUS – Multifunctional phosphate system for pharmaceutical, food and water treatment applications

1. General Introduction to Dibasic Sodium Phosphate Dodecahydrate PARENTEX PLUS

Dibasic Sodium Phosphate Dodecahydrate PARENTEX PLUS is an inorganic sodium phosphate salt with the chemical formula Na₂HPO₄·12H₂O, appearing as a white crystalline solid that is odorless and fully soluble in water.

According to international pharmacopoeias such as USP–NF and Ph.Eur., this compound is classified as a pharmaceutical excipient, primarily functioning as a buffering agent and pH adjuster in a wide range of formulation systems. The phosphate buffer system (NaH₂PO₄ / Na₂HPO₄) is one of the most important biological buffering systems due to its pKa₂ ≈ 7.2, which is close to human physiological pH (7.35–7.45). Therefore, it is extensively used in pharmaceutical, biochemical, and molecular biology applications.

Dibasic Sodium Phosphate Dodecahydrate PARENTEX PLUS is primarily applied as a phosphate buffer system and pH-adjusting excipient in pharmaceuticals, food products, and industrial water treatment systems, particularly in formulations requiring long-term chemical microenvironment stability.

2. Active Composition of Dibasic Sodium Phosphate Dodecahydrate PARENTEX PLUS

3. Key Advantages of Dibasic Sodium Phosphate Dodecahydrate PARENTEX PLUS

• Physiologically relevant phosphate buffer system: The NaH₂PO₄ / Na₂HPO₄ system (pKa₂ ≈ 7.2) provides effective buffering capacity around physiological pH, making it widely used in pharmaceutical and biological formulations.
• Pharmacopoeial compliance (USP–Ph.Eur–BP): Meets international standards for purity, including limits for heavy metals, sulfates, chlorides, and inorganic impurities according to official monographs.
• High water solubility: Forms clear, transparent solutions, facilitating easy incorporation into liquid and semi-solid formulations.
• Chemical stability: Phosphate buffers are chemically stable and minimally affected by temperature under standard storage conditions.
• Multi-industry applicability: Widely used across pharmaceuticals, food applications, and industrial water treatment, including compliance with food additive regulation E339.

4. Applications of Dibasic Sodium Phosphate Dodecahydrate PARENTEX PLUS

Pharmaceutical Applications

• Injectable solutions: Used in phosphate buffer systems to maintain stable pH in non-protein or pH-stabilized protein injectable formulations.
• Ophthalmic solutions: Adjusts pH to physiological levels to ensure ocular compatibility and reduce irritation.
• Oral solutions: Maintains pH stability to prevent chemical degradation of active ingredients.
• Effervescent tablets and soluble formulations: Participates in acid–base reactions and buffering systems within formulations.

Food Applications

• Bakery products: Helps regulate acidity and improve dough structure.
• Processed meat products: Enhances water retention capacity and improves texture.
• Beverages and processed foods: Functions as a pH regulator and emulsion stabilizer.

Water Treatment Applications

• Boiler and cooling water systems: Reduces scaling risk from CaCO₃ and MgCO₃ by controlling phosphate balance.
• Industrial water systems: Helps stabilize metal ions and minimize scale formation.

5. Commercial products using Dibasic sodium phosphate dodecahydrate PARENTEX PLUS

6. Product contact information

For further information regarding the supply of Dibasic Sodium Phosphate Dodecahydrate USP/Ph.Eur/BP PARENTEX PLUS, please contact:

• Hotline: +84 (0) 834 560 500
• Email: director@biorichgroup.com
• Website: www.biorichgroup.com
• Sample & COA Request: Please contact us via email to receive product samples and the latest Certificate of Analysis (COA).