1. General introduction to Dimethicone 

Dimethiconeis a highly biologically inert siloxane polymer widely used in pharmaceuticals, cosmetics, and personal care products as an antifoaming excipient, water-repellent agent, and emollientfor topical formulations. Owing to its hydrophobic characteristics, excellent stability profile, and superior film-forming properties, Dimethicone has become a preferred excipient for premium pharmaceutical and cosmetic formulations requiring optimized sensory performance and long-term formulation stability.

Dimethicone is manufactured under a quality management system compliant with international USP/EP standards. Typically, Dimethicone grades feature a wide viscosity range from 50 to 12,500 mm²/s, offering flexible adaptability for diverse dosage forms—from tablets and capsules to ointments and oral emulsions.

2. Material Information - Dimethicone

• Material name:Dimethicone (or Polydimethylsiloxane)
• Ingredient Category: Pharmaceutical Excipient / Active Ingredient
• CAS: 9006-65-9
• Appearance: Clear, colorless liquid
• Odor:Odorless or almost odorless
• Taste: Tasteless
• Solubility:Very soluble in ether, mineral oil, chloroform, and toluene; practically insoluble in water and ethanol
• Viscosity range:Dimethicone is a linear polymer of dimethylsiloxane with a viscosity range of 20 – 30,000 mm²/s. Commercially available grades typically range from 50 – 12,500 mm²/s.
• Stability: Heat-stable and chemically virtually inert
• Quality standards: USP/NF, EP, BP, JP, CP
• Certifications: EXCiPACT GMP, ISO 9001, Halal, Kosher

3. Key advantages of Dimethicone 

• High biological inertness and superior safety profile: Dimethicone is barely absorbed through the skin or mucous membranes, non-toxic, and carries a low risk of irritation.
• Efficient antifoaming performance in complex formulation systems: Due to its surface tension-reducing properties, Dimethicone effectively controls foam generation during both manufacturing and product application, particularly in liquid and suspension systems.
• Effective barrier formation and reduction of transepidermal water loss: Its hydrophobic nature enables Dimethicone to form a thin protective barrier on the skin surface, helping reduce transepidermal water loss and enhance moisturization performance in topical formulations.
• Smooth, non-greasy sensory feel: Dimethicone provides a silky, smooth, and non-sticky skin feel, significantly improving the sensory experience of premium cosmetic and personal care products.
• High chemical and physical stability: The material exhibits excellent resistance to oxidation and degradation under normal storage conditions while maintaining functional performance throughout the product lifecycle.
• Broad compatibility with excipient and active ingredient systems: Dimethicone demonstrates excellent compatibility with various oil phases, emulsions, and polymer systems commonly used in modern pharmaceutical and cosmetic formulations.
• Compliance with international pharmaceutical standards: The material complies with USP/EP/BP standards and is supported by EXCiPACT GMP certification, facilitating pharmaceutical product registration and export activities.
• Stable supply chain and comprehensive technical support: The product is readily available in GSP/GDP warehouses with complete documentation including COA, MSDS, TDS, and product specifications for industrial-scale manufacturing requirements.

4. Applications of Dimethicone

In pharmaceutical formulations

• Oral Liquid Formulations: Controls foam generation during processing and use of oral liquids.
• Tablets / Hard Capsules: Functions as a glidant/lubricant excipient in formulations containing sensitive active ingredients (e.g., Vitamin C).
• Emulsions / Ointments / Topical Creams: Forms a protective skin barrier, reduces transepidermal water loss, and enhances the smooth, soft skin feel. Typically incorporated into the oil phase of the formulation.

 In cosmetic formulations

• Moisturizing Creams: Creates a moisture-locking layer and improves skin softness.
• Facial Serums: Provides a smooth glide, reduces stickiness, and enhances user experience.
• Body lotions: Improves skin smoothness and helps reduce moisture loss.
• Hair care products: Forms a protective coating that improves softness, shine, and anti-frizz performance.

5. Commercial products using Dimethicone

6. Product contact information

For further information regarding Dimethicone supply capability, technical specifications, or commercial inquiries, please contact us:

• Hotline: +84 (0) 834 560 500
• Email: director@biorichgroup.com
• Website: www.biorichgroup.com
• Sample & COA Request:  Please contact us via email to request product samples and the latest Certificate of Analysis (COA).