1. General Introduction to Methacrylic acid Divinyl benzene copolymer
Methacrylic acid Divinyl benzene copolymer (commonly known as an ion exchange resin, or Polacrilex) is a cross-linked polymer of methacrylic acid and divinyl benzene. Thanks to its specific porous network structure and weak acid functional groups, this material has the ability to reversibly bind with positively charged active pharmaceutical ingredient molecules (cations).
In the pharmaceutical industry, this excipient is applied as a breakthrough solution to mask the harsh bitter taste of drugs (taste masking), improve the stability of easily degraded active ingredients, and support sustained-release drug delivery systems, providing high therapeutic efficacy and safety for users.
2. Raw Material Information of Methacrylic acid Divinyl benzene copolymer
- Raw Material Name: Methacrylic acid Divinyl benzene copolymer (Polacrilex resin)
- Material Group: Pharmaceutical Excipients / Ion exchange resin, taste masking excipient.
- Function: Taste masking, carrier for controlled release of active ingredients, active ingredient stabilizer.
- Chemical Composition: Copolymer of methacrylic acid cross-linked with divinyl benzene.
- Physical Form: Fine powder or porous granules, white to slightly yellow, odorless or with a faint odor.
- Solubility: Insoluble in water, alcohol, and most common organic solvents, not absorbed through the gastrointestinal tract.
- Quality Standards: Complies with current international pharmacopoeias (USP/Ph.Eur/BP).
The raw material is strictly controlled for:
- Particle Size and Porosity: Optimized surface area to ensure the highest level of drug loading capacity.
- Ion Exchange Capacity: Strictly controlled to ensure uniformity in binding and releasing active ingredients.
3. Advantages of the Raw Material
- Excellent Taste Masking: Thanks to its ability to tightly bind with bitter active ingredients, the excipient helps prevent their release right in the oral cavity, making it easier for patients (especially children and the elderly) to comply with treatment.
- Effective Controlled Release: The active ingredient is only released slowly when in contact with environments containing suitable exchangeable ions (such as in gastric or intestinal fluids), helping to prolong the drug's effect and reduce toxicity-causing peak concentrations.
- Improved Chemical Stability: Protects active ingredients susceptible to degradation by environmental factors (light, moisture, oxidation) by safely entrapping them within the polymer network structure.
- High Biological Safety: Because it is an insoluble polymer by nature, the material is not absorbed into the circulatory system but will be completely excreted from the body through the digestive tract.
4. Applications of Methacrylic acid Divinyl benzene copolymer
In Pharmaceuticals (Core Application)
- Manufacturing of Chewable Tablets, Lozenges, and Oral Suspensions: The most common application to eliminate the bitter taste of antibiotics, analgesics, or liquid cough and cold medications.
- Smoking Cessation Therapies: A core ingredient in smoking cessation chewing gum or lozenges (Nicotine Polacrilex), helping nicotine to be released slowly through the oral mucosa, safely reducing cravings.
- Controlled Release Drug Delivery Systems: Acts as a carrier in sustained-release tablet formulations, precisely controlling the dosage of the active ingredient introduced into the body.
In Health Supplements
- Masking the Taste of Unpleasant Nutrients: Used to bind herbal extracts, vitamins, or minerals with unpleasant tastes, applied in gummy products and children's syrups.
5. Commercial Products Using Methacrylic acid Divinyl benzene copolymer
6. Product Contact Information
For more information about the supply chain, technical specifications of Methacrylic acid Divinyl benzene copolymer or to place an order, please contact us:
- Consultation Hotline: +84 (0) 834 560 500
- Email: director@biorichgroup.com
- Website:www.biorichgroup.com
- Request for Sample/COA: Please contact us via email to request a sample and the latest Certificate of Analysis (COA) of the raw material.
