Methacrylic acid polymer with Divinyl benzene with potassium – Specialized superdisintegrant, optimizing active ingredient release for tablets

1. General introduction to Methacrylic acid polymer with Divinyl benzene with potassium 

Methacrylic acid polymer with Divinyl benzene with potassium form (commonly known as Polacrilin Potassium) is an ion-exchange resin. This is an advanced superdisintegrant specially designed to overcome the disadvantages of conventional disintegrants, typically featuring extremely strong swelling capabilities upon contact with water.

With its cross-linked structure, this material provides rapid disintegration of tablets and capsules, ensuring the maximum and timely release of active ingredients, thereby enhancing the bioavailability of pharmaceutical and dietary supplement products.

2. Information about Methacrylic acid polymer with Divinyl benzene with potassium

• Ingredient Name: Methacrylic acid polymer with Divinyl benzene with potassium
• Ingredient Group: Pharmaceutical Excipients / Superdisintegrant, Ion-exchange resin.
• Function: Superdisintegrant for fast tablet disintegration, taste masking, formula stabilization.
• Chemical Composition: Cross-linked polymer of methacrylic acid and divinylbenzene as a potassium salt.
• Form: Free-flowing porous powder, white to off-white, no characteristic odor or taste.
• Solubility: Insoluble in water and most organic solvents, but swells significantly (hydrates) upon contact with water or gastrointestinal fluids.

3. Advantages of the ingredient

• Outstanding superdisintegrant capability: The extremely fast and large volumetric swelling property upon contact with water helps tablets/capsules shatter instantly, maximizing active ingredient release.
• Effective taste masking: Thanks to the ion-exchange mechanism, the material can bind to bitter active ingredients, excellently masking unpleasant tastes, making it highly suitable for chewable or lozenge tablets.
• High safety and biological profile: The material is insoluble in the digestive tract, is not absorbed into the bloodstream, and is excreted intact from the body, ensuring absolute safety for users.
• Optimizing stability: Functions smoothly within formulations without chemically interacting with most active pharmaceutical ingredients, without affecting the hardness or stability of the tablets during storage.

4. Applications of Methacrylic acid polymer with Divinyl benzene with potassium

• In pharmaceuticals and dietary supplements (Core application): Widely used in dosage forms requiring rapid disintegration.
• Tablet and capsule manufacturing: The largest and most important application. Typically used at a low percentage (from 1% - 5%) in the formula as an ultra-fast disintegrant, compatible with wet granulation, dry granulation, and direct compression methods.
• Chewables, lozenges, and suspensions: Applied as a taste-masking agent for drugs containing antibiotics or highly bitter active ingredients, helping increase patient compliance (especially children).
• In specialized dosage forms: Applied to modify or control the release process of pharmaceutical substances in certain modified-release formulations.

5. Product contact information

For more information about the supply chain, technical specifications of Methacrylic acid polymer with Divinyl benzene with potassium, or to place an order, please contact us:

• Consulting Hotline: +84 (0) 834 560 500
• Email: director@biorichgroup.com
• Website:www.biorichgroup.com
• Sample/COA Request: Please contact us via email to request a sample and the latest Certificate of Analysis (COA) for the ingredient.