PolyOxyl 35 Castor Oil – Premium surfactant and solubilizing excipient for pharmaceuticals and cosmetics

1. General introduction to PolyOxyl 35 Castor Oil

PolyOxyl 35 Castor Oil (also known as Polyethoxylated castor oil) is a widely used nonionic surfactant and solubilizer. This material is synthesized by reacting castor oil with ethylene oxide, creating a compound with excellent emulsifying and solubilizing capabilities.

With the ability to improve the bioavailability of poorly water-soluble drugs, PolyOxyl 35 Castor Oil plays an important role in the design of modern formulations. The material helps dissolve hydrophobic active ingredients, providing uniformity, stability, and high efficiency for pharmaceutical and cosmetic products.

2. Information on PolyOxyl 35 Castor Oil

• Raw material name: PolyOxyl 35 Castor Oil (Polyethoxylated castor oil)
• Material category: Pharmaceutical excipients / Surfactants, emulsifiers, solubilizers.
• Function: Increases solubility for poorly soluble active ingredients, emulsifies, stabilizes dispersion systems.
• Chemical composition: A mixture of hydrophilic and lipophilic components formed from the esterification and etherification reaction between castor oil and ethylene oxide.
• Material form: Viscous liquid, pale yellow to yellow in color, with a characteristic mild odor.
• Solubility: Highly soluble in water, ethanol, isopropanol, and ethyl acetate. Insoluble in mineral oil.

3. Advantages of PolyOxyl 35 Castor Oil

• Superior solubilization: Completely solves the solubility problem of BCS class II and IV drugs (poorly soluble), helping to incorporate hydrophobic active ingredients into a uniform dispersion system easily.
• Improved bioavailability: Enhances the absorption of active ingredients through the gastrointestinal tract due to the ability to micellize hydrophobic molecules.
• High stability: Operates stably across a wide pH range and is minimally affected by temperature changes during formulation, helping to maintain product shelf life.
• Excellent compatibility: Perfectly compatible with many other excipients, not affecting the chemical structure of most accompanying active ingredients.

4. Applications of PolyOxyl 35 Castor Oil

In pharmaceuticals and health supplements (Core applications)

• Liquid dosage forms and soft capsules: Widely used as an emulsifier and solubilizer in formulations of oral solutions, suspensions, and soft capsules containing hydrophobic active ingredients (such as fat-soluble vitamins A, D, E, K or herbal extracts).
• Self-emulsifying systems (SEDDS/SMEDDS): Acts as the main surfactant helping the formulation self-emulsify into microemulsions upon contact with gastric digestive fluids, maximizing drug absorption.

In cosmetics and personal care

• Skin and hair care products: Applied as a solubilizer and emulsifier, helping to mix oil-based ingredients (such as essential oils, fragrances, vitamins) into a water base transparently and stably. Often found in toner, serum, lotion, and hair gel formulations.

5. Commercial products using PolyOxyl 35 Castor Oil

6. Product contact information

For more information on the supply chain, technical specifications of PolyOxyl 35 Castor Oil, or to place an order, please contact us:

• Consulting Hotline: +84 (0) 834 560 500
• Email: director@biorichgroup.com
• Website: www.biorichgroup.com
• Sample/COA Request: Please contact us via email to request a sample and the latest Certificate of Analysis (COA) of the material.