Sodium Citrate Dihydrate is the dihydrate form of trisodium citrate, a widely used pharmaceutical raw material known for its buffering, alkalinizing, and electrolyte-supporting functions. It is commonly used in oral formulations, especially oral rehydration salts (ORS). PubChem lists the substance under CAS 6132-04-3 with molecular weight 294.10.
In the pharmaceutical market, Sodium Citrate Dihydrate is relevant not only as an excipient or buffering salt but also as an active functional component in products such as oral rehydration salts and sodium citrate/citric acid oral solution. DailyMed describes Sodium Citrate and Citric Acid Oral Solution, as an oral alkalinizing buffer, while WHO/UNICEF documents include trisodium citrate dihydrate in standard ORS composition.
Sodium Citrate Dihydrate is generally identified as trisodium citrate dihydrate, with molecular formula C6H9Na3O9 and molecular weight 294.10. It is the sodium salt of citric acid and contains two molecules of water of crystallization. The compound is widely recognized in pharmaceutical and food applications as a pH-adjusting and buffering agent.
Sodium Citrate Dihydrate is used in oral rehydration salts (ORS/Oresol), where it functions as the citrate component in reduced-osmolarity electrolyte formulas. A commercial example is Oresol 245 DHG Pharma.
It is also used in oral alkalinizing solutions.
Depending on formulation strategy, Sodium Citrate Dihydrate may also be used as a buffering salt, alkalinizing component and processing aid in oral powders, granules, and liquids where pH control and electrolyte compatibility are important. This is an inference from its recognized pharmacopeial and formulation role as a citrate salt.
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