Ammonium Glycyrrhizinate is a bioactive compound extracted from the root of licorice plant (Glycyrrhiza glabra). Chemically, it is the ammonium salt of Glycyrrhizic acid - a natural saponin compound well known for its powerful anti-inflammatory and skin-soothing properties.
In the pharmaceutical and cosmetic industries, Ammonium Glycyrrhizinate is considered a high value functional ingredient. It is widely incorporated into formulations designed to reduce skin irritation, calm inflamed skin and improve the condition of sensitive skin.
Thanks to its natural origin and excellent safety profile, this ingredient is commonly used in premium skincare products, dermatological treatments and lip care formulations.
The primary active component of Ammonium Glycyrrhizinate is the ammonium salt of Glycyrrhizic acid derived from licorice root extract.
Typical technical specifications
This active compound demonstrates strong biological activity, particularly in anti-inflammatory, antioxidant and skin-conditioning functions, making it a valuable ingredient for pharmaceutical and cosmetic formulations.
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Ammonium Glycyrrhizinate offers multiple advantages in both pharmacological activity and formulation compatibility, making it one of the key functional ingredients in modern pharmaceutical and cosmetic manufacturing.
Powerful anti-inflammatory mechanism
Ammonium Glycyrrhizinate can inhibit inflammatory mediators such as prostaglandins and cytokines, helping to reduce symptoms of inflammation including redness, swelling, and irritation. This mechanism makes it highly effective in dermatological formulations and products designed for sensitive skin.
Skin-soothing and anti-irritation properties
The ingredient helps stabilize the skin barrier and reduce sensations of burning, itching, and discomfort caused by environmental stressors or cosmetic ingredients. For this reason, Ammonium Glycyrrhizinate is frequently used in formulations for sensitive or damaged skin.
Antioxidant protection
The glycyrrhizic acid component of Ammonium Glycyrrhizinate has antioxidant properties that help neutralize free radicals. This protective effect helps prevent oxidative stress caused by UV exposure, pollution, and other environmental factors that can damage skin cells.
High formulation compatibility
Ammonium Glycyrrhizinate has excellent water solubility and can be easily incorporated into various formulation systems, including:
This flexibility allows manufacturers to apply the ingredient across a wide range of cosmetic and pharmaceutical products.
Natural origin and high safety profile
Derived from licorice root extract, Ammonium Glycyrrhizinate is a naturally sourced ingredient with a long history of safe use in pharmaceutical and cosmetic applications. Its safety profile makes it particularly suitable for products intended for sensitive skin.
Due to its diverse biological activities, Ammonium Glycyrrhizinate is widely used in both pharmaceutical and cosmetic products:
Dermatological anti-inflammatory treatments
In dermatological pharmaceuticals, Ammonium Glycyrrhizinate is commonly used in products designed to support the treatment of conditions such as dermatitis, eczema, and allergic skin reactions. The ingredient helps reduce redness, inflammation, and skin irritation.
Skincare products for sensitive skin
Ammonium Glycyrrhizinate is frequently included in skincare formulations designed for sensitive or reactive skin. It improves skin tolerance and helps reduce irritation caused by environmental or cosmetic factors.
Lip care and lipstick formulations
In lip care products such as lip balms, lipsticks, and lip glosses, Ammonium Glycyrrhizinate provides several benefits:
These benefits enhance the overall user experience of lip care products.
Acne care products
Due to its anti-inflammatory properties, Ammonium Glycyrrhizinate is often used in:
Cleansing and skin recovery products
This ingredient is also commonly found in facial cleansers, soothing masks, and post-treatment skin recovery products, helping maintain balanced, healthy skin.
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Email: biopharma@biorichpharma.com
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