PEG 3350 – High-Quality Pharmaceutical Raw Material & Osmotic Laxative Solution from India

1. General Introduction to PEG 3350

PEG 3350 (Polyethylene Glycol 3350 or Macrogol 3350) is a polymer compound widely used in the medical and pharmaceutical fields. In medical treatment, PEG 3350 stands out as a safe osmotic laxative, helping to retain water in the intestinal tract to soften stool, thereby effectively treating constipation without causing dependence or irritating the intestinal mucosa. In addition, it is an important excipient that acts as a solubilizer, binder, and lubricant in pharmaceutical manufacturing.

The raw material is manufactured by Nitika Pharmaceutical Specialities Pvt. Ltd. (India), one of the leading reputable manufacturers of pharmaceutical excipients and Active Pharmaceutical Ingredients (APIs) in India. With modern technology and a strict quality control process, Nitika's PEG 3350 achieves optimal purity, complies with international pharmacopoeia standards, and ensures high safety and efficacy for all formulations.

2. PEG 3350 Raw Material Information

• Material Name: PEG 3350 / Polyethylene Glycol 3350 / Macrogol 3350.
• Manufacturer: Nitika Pharmaceutical Specialities Pvt. Ltd.
• Origin: India.
• Material Category: Active Pharmaceutical Ingredient (API) / Pharmaceutical Excipient.
• Function: Osmotic laxative (as an API), binder, lubricant, film-coating excipient, and solvent to enhance the solubility of poorly soluble drugs.
• Chemical Composition: A polymer of ethylene oxide and water, with an average molecular weight of 3350.
• Form: Powder or waxy flakes, white or almost white, odorless or with a very faint characteristic odor.
• Solubility: Very soluble in water, freely soluble in ethanol and polar organic solvents, insoluble in fatty ethers and mineral oils.
• Quality Standards: Complies with strict international pharmacopoeia standards such as USP, BP, and EP.

The material is strictly controlled for:

• Molecular Weight: Ensures the standard average molecular weight of 3350 to maximize water retention in the colon without being absorbed into the bloodstream.
• Purity and Safety: Strict control of related impurities, free ethylene oxide, 1,4-dioxane, and heavy metal limits, ensuring absolute safety for users (including children).
• Microbiology: Meets strict pharmacopoeial standards for microbial limits.

3. Advantages of Nitika's PEG 3350

• Safe Physical Mechanism of Action: PEG 3350 is not absorbed through the gastrointestinal tract; it works solely by creating osmotic pressure to draw water into the colon. Because of this, it is safe for long-term use, has minimal side effects, does not cause intestinal cramping, and is highly well-tolerated.
• International Standard Quality: Manufactured by Nitika—a GMP-certified facility in India—ensuring high batch-to-batch consistency and excellent stability during storage.
• Versatile in Formulation: Thanks to its superior physicochemical properties, PEG 3350 is easily incorporated into various dosage forms, ranging from powders for oral solutions to tablets and capsules.

4. Applications of PEG 3350

In Pharmaceuticals (Core Applications)

• Gastrointestinal Treatment (API): Acts as the main active ingredient for medications treating constipation (acute and chronic) and bowel preparation solutions prior to endoscopy or intestinal surgery.
• Pharmaceutical Excipient: Applied as a binder in tableting, a plasticizer in film coatings, an ointment base, or to enhance the bioavailability of poorly soluble active ingredients.
• Common Dosage Forms: Powders for oral suspension, oral solutions, tablets, capsules, and suppositories.

In Health Supplements and Cosmetics

• Healthcare Products: Applied in digestive support formulas.
• Cosmetics: Acts as a film-forming agent, humectant, and viscosity controller in creams and lotions.

5. Commercial Products Using PEG 3350

6. Product Contact Information

For more information about the supply chain, technical specifications of PEG 3350, or to place an order, please contact us:

• Consultation Hotline: +84 (0) 834 560 500
• Email: director@biorichgroup.com
• Website:www.biorichgroup.com
• Sample/COA Request: Please contact us via email to request samples and the latest Certificate of Analysis (COA) for the material from the manufacturer, Nitika Pharmaceutical Specialities Pvt. Ltd.